Knots of discord in our family, lack of understanding between parents and children, disrespect, violence, the knots of deep hurts between husband and wife, the absence of peace and joy at home. They are also the knots of anguish and despair of separated couples, the dissolution of the family, the knots of a drug addict son or daughter, sick or separated from home or God, knots of alcoholism, the practice of abortion, depression, unemployment, fear, solitude. . .
H/T to Denise.